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antibiotics takes a lot of time and
do not evaluate the antibiotic market
Professor Shim says, ¡°Despite the
money; but pharmaceutical companies
as profitable. Even if there is a problem
system, however, the issue of antibiotic
are commercial interest groups. Then,
at just a single stage of these complex
abuse,includingthemisuseofantibiotics
between developing antibiotics and
processes, they have to scrap the whole
in the medical community, is ongoing
developing drugs for chronic diseases
project. Furthermore, despite such risks
andrequiresrelentlessefforts.¡±
such as high blood pressure or diabetes,
and investments, there are not many
Solutions are also needed for livestock
or sexual functional improvements,
patients?customers?because although
antibiotics, which contribute greatly to
which one will they prefer? Let me
antibiotic-resistant bacteria are a serious
the resistance of microbes. Professor
detail: high blood pressure drugs,
issue, there are not so many yet. Thus,
Ko says, ¡°The perception itself should
diabetes drugs, and drugs for sexual
even if they develop it, they can hardly
change. Administering antibiotics to
development are the ones taken for life.
expectenoughreturns.¡±
livestockisnotactuallyduetoinfection,
However, antibiotics are only taken
but because antibiotics act as a kind
whenpeoplearesick;people donotbuy
of growth booster, which is a problem
them anymore when they are not sick.
because antibiotic-resistant bacteria
This means that there is no room for
Solution
from livestock can infect humans. Thus,
enough business continuity. In addition,
we need to monitor the prescription of
antibiotic resistance is technically a
unnecessary antibiotics for livestock
resultofnaturalselection,theDarwinian
morethoroughly,andweneedincentives
State-levelresolution:financial
theory. To prevent such a fundamental
for the industry that do not use
support&policylegislation
part of the earth is extremely difficult,
antibiotics.¡±
andwhatisworse?eveniftheymadeit,
The government needs to take the
He also emphasizes the government¡¯s
itbecomestotallyuselessonceresistance
lead in resolving the antibiotic-resistant
roleininvestinginantibiotics.¡°Ibelieve
develops.Thesearefundamentalreasons
bacteria response issue as it is highly
that the issue of developing antibiotics
the industry feels reluctant to invest in
complicated due to conflicting interests
should not be approached only in terms
it.¡±
in various private sectors. As a part of
of the interests of the private sector.
Professor Park argues that the
the effort, South Korea is conducting
It is a matter for governments to step
complexityoftheantibioticdevelopment
multi-ministerial joint project of One
up, and it will only be solved if it is
process also greatly contributes to the
Health antibiotic resistance under the
approached in the public interest.¡± He
difficulties of attracting investment.
presidencyoftheKoreaDiseaseControl
also cited Britain as an exemplary case
¡°There are three stages of drug
and Prevention Agency to bring the
abroad. ¡°In the Longitude Prize of the
development,¡± he says, ¡°Phase 1,
power of each ministry together and
U.K., antibiotic resistance was chosen
screening: find an effective candidate
jointly respond to antibiotic resistance
as the target. The award rewards 10
material. Phase 2, testing for toxicity or
bacteria. Various government-affiliated
million pounds (US$ 14 million) for the
non-toxicity (preclinical-animal testing
ministries, including the Ministry of
people who contribute to and identify
phase, this phase alone can take more
Food and Drug Safety, the Ministry of
antibiotic resistance matter. As such,
than a year), and then phase 3; but this
Agriculture, Food and Rural Affairs,
the government has to provide long-
phase3isdividedintothreestagesagain:
the Ministry of Environment, and
term support, and cooperation between
first, toxicity test for humans; second,
the Ministry of Science and ICT, are
countriesisnecessary.¡±
checkingtheappropriatedoseforusage;
participating in research on antibiotic
third,expandingtherangeofthetestfor
resistance.
commercialization with control groups.
¡°In fact, the responsible governmental
Rolesformedicalsystem:
Ultimately,todevelopanantibioticdrug
institute, called Health Insurance
spearheadedenlightenment&
usuallytakesfivetotenyears.Andthen,
Review & Assessment Service is
reconsiderationofprescription
one such antibiotic development costs
strictly reviewing prescriptions so that
at least $500 million to $1 billion. Not
the Medicare Corporations do not pay
Antibiotic over-prescriptions due to
surprisingly, pharmaceutical companies
doctors for over-prescribed drugs.¡±
an excessive prevention ethos should be
20
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