총 44페이지
20페이지 본문시작
Cover Story
resistant to every antimicrobial drug
Evolutionofantibiotic-resistant
ⓒIstock
that humankind currently possesses. To
bacteria
fight these new and unbeatable enemies,
The most urgent antibiotic drug
the development of novel antimicrobial
problem is that their improper usage
drugsisdesperatelyneeded.
encouragestheemergenceofthebacteria
Nonetheless, the newly developed
which are resistant to the medicines.
antibiotics are substantially scarce,
The discovery of Penicillin in 1928
in comparison to the drugs falling
enormously contributed to the medical
inefficientbecauseofantimicrobialdrug
system,savinghundredsofthousandsof
resistance. Professor Ko says, “It has
▲Everyantibioticdrugwehavecanbecome
lives. Since the 1950s, when antibiotic
been over 20 years since antimicrobial
uselessiftheabuseofthedrugscontinues.
drugs were largely distributed, though,
drug development was criticized as
resistance to such germs has noticeably
where we have to risk our life to cure
sluggish. Since the late 1990s, the
developed. Despite being a panacea for
a trivial wound could come true if
number of antibiotics that are permitted
decades,nowitrequiresalternativesthat
antibiotic-resistance becomes rampant
anew has plummeted, as a matter of
musttakeitsplacetofightthegerms.
andthereremainsnodrugtouse,”warns
fact. To cope with the appearance of
It is well known that use of antibiotics
Professor Ko Kwan-soo, the director of
antibiotic-resistant bacteria, global
brings about tolerance to them and
the Antimicrobial Resistant Pathogen
researchanddevelopmentofnoveldrugs
thus they lose their original efficacy.
Research Lab at School of Medicines
is imperative. In reality, however, the
However,amisunderstandingisglobally
of SungKyunKwan University. “In the
paceofdevelopmentisfallingbehindthe
pervasive: “People think that when we
19th century or the early 20th century,
speedofbacterialevolution.”
use antibiotics, ‘we’ become resistant
before antibiotics were commercialized,
to antibiotics. This is wrong,” Professor
people died more because they could
Park explains. “As a matter of fact,
not cure their wounds which led to
‘germs,’whichsurvivedthedrugsevolve
severe infections, than because of
Cause
into resistant bacteria; injection of
actual combat. Not until Penicillin
antibiotic drugs triggers the ‘evolution
was discovered, did people become
of harmful germs,’ consequently. When
able to treat such illnesses. However,
Antibioticabusebymedical
Penicillin was first administered, for
antibiotic-resistance can devastate the
practitioners
example, it showed efficacy to most
efforts and results that the human race
bacteria. The problem is, they are living
has accomplished for about a hundred
Excessive antibiotic prescription is
things, so they generate surviving
prevalent, mainly resulting from the
years.”
mutants. Another matter is that it kills
tradition of the medical community. It
bacterial flora, the good microbes.
canalsobefoundinthereactionagainst
There is a more noteworthy problem
COVID-19; antibiotics have generally
Tardyantimicrobialdrugs
than just the beneficial germs dying.
been administered even in the early
development
To put it simply, germs compete for
stagesofthenovelcoronavirusinfection.
space with each other. When antibiotics
Since the first discovery of antibiotics,
However, the results of a clinical trial
destroy the bacterial flora, their space
mankindhasadministeredantimicrobial
onJanuary25,2021,releasedbyOxford
is taken over by the surviving resistant
drugs beyond count?this has led to
University, revealed that antibiotics
germs; therefore, they are given the
the evolution of microbes to an extent
treatment previously used in the early
best environment in which to flourish.
that used to be unimaginable for the
phases of the COVID-19 diagnosis
Combined the two processes, antibiotic-
past million years. As a result, the
did not work at all. This unnecessary
resistancedevelopsdramatically.”
world has already reached a tipping
abuse of antibiotics makes it difficult
Experts concede that this issue can
point with the emergence of super-
to anticipate treatment effects, and it
put us at ground-zero. “The situation
bacteria, those microbes which are
is highly likely to lead to unexpected
18
www.theargus.org
resistant to every antimicrobial drug
Evolutionofantibiotic-resistant
ⓒIstock
that humankind currently possesses. To
bacteria
fight these new and unbeatable enemies,
The most urgent antibiotic drug
the development of novel antimicrobial
problem is that their improper usage
drugsisdesperatelyneeded.
encouragestheemergenceofthebacteria
Nonetheless, the newly developed
which are resistant to the medicines.
antibiotics are substantially scarce,
The discovery of Penicillin in 1928
in comparison to the drugs falling
enormously contributed to the medical
inefficientbecauseofantimicrobialdrug
system,savinghundredsofthousandsof
resistance. Professor Ko says, “It has
▲Everyantibioticdrugwehavecanbecome
lives. Since the 1950s, when antibiotic
been over 20 years since antimicrobial
uselessiftheabuseofthedrugscontinues.
drugs were largely distributed, though,
drug development was criticized as
resistance to such germs has noticeably
where we have to risk our life to cure
sluggish. Since the late 1990s, the
developed. Despite being a panacea for
a trivial wound could come true if
number of antibiotics that are permitted
decades,nowitrequiresalternativesthat
antibiotic-resistance becomes rampant
anew has plummeted, as a matter of
musttakeitsplacetofightthegerms.
andthereremainsnodrugtouse,”warns
fact. To cope with the appearance of
It is well known that use of antibiotics
Professor Ko Kwan-soo, the director of
antibiotic-resistant bacteria, global
brings about tolerance to them and
the Antimicrobial Resistant Pathogen
researchanddevelopmentofnoveldrugs
thus they lose their original efficacy.
Research Lab at School of Medicines
is imperative. In reality, however, the
However,amisunderstandingisglobally
of SungKyunKwan University. “In the
paceofdevelopmentisfallingbehindthe
pervasive: “People think that when we
19th century or the early 20th century,
speedofbacterialevolution.”
use antibiotics, ‘we’ become resistant
before antibiotics were commercialized,
to antibiotics. This is wrong,” Professor
people died more because they could
Park explains. “As a matter of fact,
not cure their wounds which led to
‘germs,’whichsurvivedthedrugsevolve
severe infections, than because of
Cause
into resistant bacteria; injection of
actual combat. Not until Penicillin
antibiotic drugs triggers the ‘evolution
was discovered, did people become
of harmful germs,’ consequently. When
able to treat such illnesses. However,
Antibioticabusebymedical
Penicillin was first administered, for
antibiotic-resistance can devastate the
practitioners
example, it showed efficacy to most
efforts and results that the human race
bacteria. The problem is, they are living
has accomplished for about a hundred
Excessive antibiotic prescription is
things, so they generate surviving
prevalent, mainly resulting from the
years.”
mutants. Another matter is that it kills
tradition of the medical community. It
bacterial flora, the good microbes.
canalsobefoundinthereactionagainst
There is a more noteworthy problem
COVID-19; antibiotics have generally
Tardyantimicrobialdrugs
than just the beneficial germs dying.
been administered even in the early
development
To put it simply, germs compete for
stagesofthenovelcoronavirusinfection.
space with each other. When antibiotics
Since the first discovery of antibiotics,
However, the results of a clinical trial
destroy the bacterial flora, their space
mankindhasadministeredantimicrobial
onJanuary25,2021,releasedbyOxford
is taken over by the surviving resistant
drugs beyond count?this has led to
University, revealed that antibiotics
germs; therefore, they are given the
the evolution of microbes to an extent
treatment previously used in the early
best environment in which to flourish.
that used to be unimaginable for the
phases of the COVID-19 diagnosis
Combined the two processes, antibiotic-
past million years. As a result, the
did not work at all. This unnecessary
resistancedevelopsdramatically.”
world has already reached a tipping
abuse of antibiotics makes it difficult
Experts concede that this issue can
point with the emergence of super-
to anticipate treatment effects, and it
put us at ground-zero. “The situation
bacteria, those microbes which are
is highly likely to lead to unexpected
18
www.theargus.org
20페이지 본문끝
메뉴
현재 포커스의 아래내용들은 동일한 컨텐츠를 가지고 페이지넘김 효과및 시각적 효과를 제공하는 페이지이므로 스크린리더 사용자는 여기까지만 낭독하시고 위의 페이지이동 링크를 사용하여 다음페이지로 이동하시기 바랍니다.