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Cover Story
Whatisanantimicrobialdrug?
An antimicrobial drug is a substance that kills or controls the growth of
ⓒIstock
microbes in the body. Two of the most well-known antimicrobial drugs are
antibiotics,whichkillbacteria,andantiviraldrugsthatinterruptthegrowthof
viruses. An effective antimicrobial drug includes selective toxicity: it affects
onlypathogenslikeharmfulbacteriaorvirusesandnotus,theirreservoirs.
Since the development of Penicillin, the first antibiotic and first antimicrobial
drug, in 1928, thousands of kinds of antibiotics have been discovered.
However, because most materials have serious toxicity or cannot be
▲Anantibioticisthemosttypicaltypeof
absorbed into our bodies, it is known that only less than 1 percent of
antimicrobialdrugs.Antibioticskillbacteria,but
antimicrobials are usable. Nevertheless, these well-sorted substances
cannotaffectviruses.
demonstratetheirmarvelouseffectivenessinthecureofinfectiousdiseases.
Problem
and necessary germs to our body live?
autoimmunedisease,whichisaninterior
called bacterial flora?antibiotics can
disorder causing our immune system
break the balance of the microbes by
to attack our body,” says Park Joong-
killingthegoodones.”
chan, a professor in the Department
Healthdeteriorationresulting
When beneficial microbes are
of Bioscience and Biotechnology at
fromantibioticsabuse
damaged, our body can, accordingly,
HUFS. He adds, “The digestive system
On the Internet, one can easily come
be harmed. Moreover, in some cases, it
is especially susceptible to such side-
across people who suffer from nausea,
leads to a significant illness. “Loss of
effects,andthusmanypatientswhohave
stomachache, or diarrhea because of
bacterial floras can trigger not only the
takenantibioticsforalongtimeareoften
antibiotic intake. Antibiotics are usually
malfunction of metabolism, but also an
witnessedtohavedigestivetroubles.”
prescribed when visiting a clinic for the
treatment of common diseases such as
MedicineWise
the cold and food poisoning, as well as
medical procedures that have nothing to
dowiththecureofdiseaseslikecosmetic
ⓒNPS
surgery, dental work or dermatologic
treatment. After consuming the drugs,
however, many experience side-effects.
Shim Won-sik, Chair of the College
of Pharmacy at Gachon University
explains, “Like when we eat food,
antibiotics go down through the throat
and are absorbed in the small intestine.
This absorption enables antibiotics to
spread from the small intestine, blood
vessels, and then to the entire body via
the blood. But here is the thing: in this
process,antibioticsubstancescouldflow
intoundesiredparts.Forexample,inthe
▲Thegeneralsymptomsofanantibioticside-effectoccurbylackingthebalanceofinteriorgermsdueto
intestines, where most of the beneficial
antibioticintake.
17
MARCH 2021
Whatisanantimicrobialdrug?
An antimicrobial drug is a substance that kills or controls the growth of
ⓒIstock
microbes in the body. Two of the most well-known antimicrobial drugs are
antibiotics,whichkillbacteria,andantiviraldrugsthatinterruptthegrowthof
viruses. An effective antimicrobial drug includes selective toxicity: it affects
onlypathogenslikeharmfulbacteriaorvirusesandnotus,theirreservoirs.
Since the development of Penicillin, the first antibiotic and first antimicrobial
drug, in 1928, thousands of kinds of antibiotics have been discovered.
However, because most materials have serious toxicity or cannot be
▲Anantibioticisthemosttypicaltypeof
absorbed into our bodies, it is known that only less than 1 percent of
antimicrobialdrugs.Antibioticskillbacteria,but
antimicrobials are usable. Nevertheless, these well-sorted substances
cannotaffectviruses.
demonstratetheirmarvelouseffectivenessinthecureofinfectiousdiseases.
Problem
and necessary germs to our body live?
autoimmunedisease,whichisaninterior
called bacterial flora?antibiotics can
disorder causing our immune system
break the balance of the microbes by
to attack our body,” says Park Joong-
killingthegoodones.”
chan, a professor in the Department
Healthdeteriorationresulting
When beneficial microbes are
of Bioscience and Biotechnology at
fromantibioticsabuse
damaged, our body can, accordingly,
HUFS. He adds, “The digestive system
On the Internet, one can easily come
be harmed. Moreover, in some cases, it
is especially susceptible to such side-
across people who suffer from nausea,
leads to a significant illness. “Loss of
effects,andthusmanypatientswhohave
stomachache, or diarrhea because of
bacterial floras can trigger not only the
takenantibioticsforalongtimeareoften
antibiotic intake. Antibiotics are usually
malfunction of metabolism, but also an
witnessedtohavedigestivetroubles.”
prescribed when visiting a clinic for the
treatment of common diseases such as
MedicineWise
the cold and food poisoning, as well as
medical procedures that have nothing to
dowiththecureofdiseaseslikecosmetic
ⓒNPS
surgery, dental work or dermatologic
treatment. After consuming the drugs,
however, many experience side-effects.
Shim Won-sik, Chair of the College
of Pharmacy at Gachon University
explains, “Like when we eat food,
antibiotics go down through the throat
and are absorbed in the small intestine.
This absorption enables antibiotics to
spread from the small intestine, blood
vessels, and then to the entire body via
the blood. But here is the thing: in this
process,antibioticsubstancescouldflow
intoundesiredparts.Forexample,inthe
▲Thegeneralsymptomsofanantibioticside-effectoccurbylackingthebalanceofinteriorgermsdueto
intestines, where most of the beneficial
antibioticintake.
17
MARCH 2021
19페이지 본문끝
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